B-NDG H2-K1/H2-D1 KO mice_Biocytogen Pharmaceuticals (Beijing) Co., Ltd._Biocytogen, drug development, antibody discovery

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동물/세포 모델

동물/세포모델

Immunodeficient Mice/Rats

Immunodeficient (B-NDG) Mice

Text

B-NDG H2-K1/H2-D1 KO mice

Strain Name	NOD.CB17-Prkdc^scidIL2rg^{tm1 Bcgen}H2-K1^{tm1 Bcgen}H2-D1^{tm1 Bcgen}/Bcgen	Common Name	B-NDG H2-K1/H2-D1 KO mice
Background	B-NDG	Catalog number	112256
Aliases	H2-K1: H-2K, H-2K(d), H2-D1, H2-K, K-f H2-D1: H-2D, H2-D, H2-K1

Protein expression analysis

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Strain specific H2-Kb/H2-Db (α chain of MHC-I molecule) expression analysis in B-NDG mice and B-NDG H2-K1/H2-D1 KO mice by flow cytometry. Bone marrow, spleen and blood were collected from B-NDG mice and B-NDG H2-K1/H2-D1 KO mice, and analyzed by flow cytometry. Mouse H-2Kb/H-2Db was only detectable in B-NDG mice but not in B-NDG H2-K1/H2-D1 KO mice.